The gut — the second brain of humans

The most important thing:

  • What is the link between the balance of gut microflora and mental health?
  • How do synbiotics support cognitive function?
  • A diet rich in synbiotics
  • The future of probiotics

You may have heard the phrase 'butterflies in your stomach' when you're nervous, excited, or even in love. Or perhaps you've felt anxiety literally settle in your stomach as a knot.

These expressions are far from mere metaphors. There is a deep and incredible connection between gut health and mental well-being. The gastrointestinal system plays a key role in regulating mood, behaviour, and even cognitive function.

When the microbiome suffers, so does the psyche.

The human gut contains trillions of microorganisms—bacteria, viruses, fungi—collectively known as the gut microbiome. This living world is like an ecosystem that constantly communicates with our body. The microbiome doesn't just digest food and synthesise vitamins. It is actively involved in the production of neurotransmitters such as serotonin, dopamine, and GABA (gamma-aminobutyric acid) — all of which are crucial for mental health.

Up to 90% of the serotonin in the human body is produced in the gut, not the brain. This is a neurotransmitter known as the 'happiness hormone'. Furthermore, the gut flora communicates with the brain via the so-called gut-brain axis, using neural pathways (mainly the vagus nerve), hormones, and immune signals.

An imbalance in the gut microbiome — a condition called dysbiosis — can lead to various health problems, including depression, anxiety, chronic fatigue, and even cognitive decline. This can happen due to:

  • Excessive use of antibiotics
  • Poor diet (high in sugars and low in fibre)
  • Chronic stress
  • Lack of sleep

Synbiotics — food for the mind

Synbiotics combine two key elements:

  • Probiotics – live bacteria that colonise the gut and restore the microbiological balance
  • Prebiotics – non-digestible fibres that serve as food for probiotics, increasing their effectiveness

Synbiotics can be formulated in two ways: complementary synbiotics, in which the probiotic and prebiotic act independently, and synergistic synbiotics, in which the prebiotic is selectively utilised by the probiotic, leading to a stronger effect.

Thus, synbiotics:

  • Improve bowel motility and regularity
  • Reduce bloating, wind and discomfort
  • Restore the microbiome after antibiotic therapy
  • Protect the intestinal mucosa from pathogenic bacteria
  • Improve the absorption of B vitamins and vitamin K

Research shows that synbiotics can have a positive effect on mental health. The combined intake of probiotics and prebiotics is more effective than taking them separately, as prebiotics support the survival and multiplication of probiotics in the gut. This leads to improved neurotransmitter production and a reduction in inflammatory processes associated with mental disorders. For example, certain probiotic strains, such as Lactobacillus rhamnosus and Bifidobacterium longum, have been linked to a reduction in symptoms of anxiety and depression. Some neurologists even call the gut "the new front line" in the fight against mental illnesses such as depression, PTSD, and bipolar disorder. A study in the Journal of Functional Foods shows that participants with moderate depression who took a synbiotic supplement for 8 weeks experienced a significant reduction in anxiety symptoms and an improvement in sleep quality.

The Gut-Brain Axis: How the Gut Affects Mental Health

The gut and brain are connected via the gut-brain axis, a communication network that includes nerve signals, hormones, and immune molecules.

The gut-brain axis is a two-way communication system between the central nervous system and the gut microbiota. This connection is achieved through neural pathways, hormones, and immune signals. Gut bacteria can influence the production of neurotransmitters that regulate mood and behaviour.

Synbiotics help to keep this axis healthy and active by:

  • Supporting the production of serotonin and dopamine
  • Suppressing inflammatory processes associated with anxiety and depression
  • Reducing cortisol, the stress hormone
  • Improving sleep and concentration
  • Reducing symptoms of anxiety and mild depression

B-Protect – a modern synbiotic for the modern person

B-Protect is a synbiotic product with a formula that combines selected probiotic strains and balanced prebiotics. Thanks to them, it maintains gut balance during times of stress and when taking medication, and also improves immune defence and the function of the digestive system. B-Protect can be part of a holistic approach to managing anxiety and fatigue, helping you to cope with everyday stress, improve mental performance, and support overall emotional well-being.

Its formula is particularly suitable for people with busy lifestyles, and it is also recommended for use with antibiotics or for stomach discomfort associated with an imbalance in the gut microbiome.

Foods rich in natural synbiotics: a natural ally for the gut and brain

Can diet also affect mood? The answer is yes, and not just when you treat yourself to something sweet as a reward after a stressful day. A proper diet is key to gut health and, as we already know, to mental resilience. Here's how to include a combination of probiotic and prebiotic foods in a varied diet:

Probiotics — live bacteria with beneficial properties:

  • Yoghurt with live cultures — especially beneficial if homemade or organic, rich in Lactobacillus bulgaricus and Streptococcus thermophilus.
  • Kefir — milk- or water-based, containing dozens of bacterial and yeast strains, excellent for microbiome diversity.
  • Kimchi — a fermented Korean side dish with a spicy flavour, offering Lactobacillus plantarum and a high amount of antioxidants.
  • Sauerkraut – rich in enzymes and lactobacilli.
  • Tempe and natto – Japanese fermented soy products, an excellent source of both probiotics and vitamin K2, which is important for bone and heart health.

Prebiotics – "food" for the good bacteria:

  • Garlic and onions – contain inulin and fructooligosaccharides, which feed the beneficial flora.
  • Orange and asparagus – rich in fibre, which stimulates the growth of bifidobacteria.
  • Bananas (especially green) — a source of resistant starch, which reaches the colon undigested and feeds the bacteria.
  • Chicory – its root contains the highest amount of inulin of all plants.
  • Oats – contain beta-glucans and resistant starch, which are beneficial for both the microbiome and cholesterol.
  • Wholegrains – as well as being rich in fibre, they maintain a feeling of fullness and provide long-lasting energy.

Personalised probiotics – the future is here

The science of the microbiome is developing at a great pace. More and more scientists are interested in so-called 'personalised probiotics', where probiotics are selected according to the patient's individual microbiome.

Psychobiotic therapies are also being developed, which combine probiotics with existing antidepressants to increase their effectiveness and reduce side effects. New biotechnologies are even creating synthetic probiotics programmed to produce specific neurotransmitters directly in the gut.

In the future, it is entirely possible that the personal microbiome will become a major factor in the diagnosis and treatment of mental illness.

Intelligent gut care is mind care

Synbiotics are not just another fad in healthy eating. They are a genuine tool for maintaining internal balance, which directly affects our mood, concentration, and ability to cope with stress. In a world where mental health is increasingly important, synbiotics are the bridge between the gut and the mind that is worth maintaining.

Sources:
  1. Healthline
  2. NCBI
  3. PubMed Central (PMC)
  4. ScienceDirect
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