Folacid Meta is a new generation of bioactive folic acid: calcium L-methylfolate, which is ready to be directly absorbed by the body, including in the presence of MTHFR mutation gene, which disrupts the metabolism of ordinary folic acid. Folacid Meta contributes to a higher folate content in the future mother’s body. Low folate levels are a risk factor for the development of fetal neural tube defect Spina Bifida[2]. 

Folacid Meta supplies the necessary daily dose of folic acid for balanced processes in the body, reduces the levels of harmful homocysteine, which damage the cardiovascular and nervous systems and promotes the synthesis of neurotransmitters in the brain. [4], [5, [6] 

* RI – reference intakes

[1] Geisel, Janet PhD, FNP Folic Acid and Neural Tube Defects in Pregnancy, The Journal of Perinatal & Neonatal Nursing: October 2003 – Volume 17 – Issue 4 – p 268-279

[2] R. Douglas Wilson, R. Douglas Wilson, François Audibert, Pre-conception Folic Acid and Multivitamin Supplementation for the Primary and Secondary Prevention of Neural Tube Defects and Other Folic Acid-Sensitive Congenital Anomalies, Journal of Obstetrics and Gynaecology Canada,

[3] Ibrahim, Zakia & Abd, Seham & Mikhail, Hind & Sc, M & Khattab, Maged. (2014). Assessment of Adherence to Iron and Folic Acid Supplementation and Prevalence of Anemia in Pregnant Women.

[4] Wald DS, Bishop L, Wald NJ, et al. Randomized Trial of Folic Acid Supplementation and Serum Homocysteine Levels. Arch Intern Med. 2001;161(5):695–700. doi:10.1001/archinte.161.5.695

[5] Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. Journal of Psychopharmacology. 2005;19(1):59-65. doi:10.1177/0269881105048899

[6] L-Methylfolate Calcium Supplementation in Adolescents and Children: A Retrospective Analysis (4226),Michelle Rainka, Traci Aladeen, Erica Westphal, Jessica Greger, Jacqueline Meane, Rachael Wojcik, Francis Gengo, Horacio Capote, Neurology Apr 2020, 94